Comprehensive Bioanalytical Services to support your pharmacokinetic and pharmacodynamic assessment
Admescope provides comprehensive quantitative bioanalytical services (non-GLP) for a full spectrum of drug modalities, including small molecules, peptides, oligonucleotides, antibodies, and antibody-drug conjugates (ADCs). Our capabilities go beyond the test compound analysis, we also determine various biomarkers to support your PK/PD assessment.
While our primary focus is on solving challenging cases through thorough, structure- and matrix-based analytical method development, we also routinely perform analyses via method transfer.
Our bioanalytical services are available as part of full in vivo DMPK packages or as standalone analysis for samples provided by our customers. To facilitate the process, our import permit for biological samples covers a wide range of species, ensuring smooth project execution. For cases requiring a specific permit (e.g., CITES-regulated species), we handle applications with local authorities. We are also happy to assist with shipment logistics when needed.
Our state-of-the-art instrumentation—including LC-MS/MS and LC-HR/MS systems—is selected based on the specific needs of each study. Given the diversity of test compound chemistries and the complexity of biological matrices, we maintain a broad analytical toolkit covering the full range of chromatographic techniques (reverse phase, HILIC, chiral). Sample preparation methods range from simple precipitation to advanced solid-phase extraction combined with chemical derivatization. Besides LC-MS analysis, which is applied for both small molecules and biologics, the analytical capabilities include qPCR and ELISA, and we can support you with bioanalysis of samples containing radiolabeled compounds as well.
Reach out to the team to discuss more!
